Impact of Intestinal Microbial Communities upon Health

作者: Harry J. Flint , Sylvia H. Duncan , Petra Louis

DOI: 10.1007/978-3-642-21680-0_18

关键词:

摘要: The microbial community of the human large intestine plays an important role in nutrition and health. Molecular analyses have revealed diversity gut bacteria; although some dominant species are abundant most individuals, humans show considerable inter-individual variation strain composition their intestinal microbiota. It is helpful therefore to define broad functional groups (‘clubs’) that share one or more characteristics interest. This approach has been applied formation by fermentation short chain fatty acids actively absorbed host as energy sources. A combination targeted molecular detection information on cultured isolates helping reveal impact diet upon responsible for particular dietary carbohydrates butyrate, should provide basis theoretical modelling this complex community.

参考文章(35)
Cecil W. Forsberg, K.-J. Cheng, Bryan A. White, Polysaccharide Degradation in the Rumen and Large Intestine Gastrointestinal Microbiology. pp. 319- 379 ,(1997) , 10.1007/978-1-4615-4111-0_10
R. I. Mackie, Bryan A. White, Gastrointestinal ecosystems and fermentations Chapman & Hall. ,(1997)
W E Moore, L H Moore, Intestinal floras of populations that have a high risk of colon cancer. Applied and Environmental Microbiology. ,vol. 61, pp. 3202- 3207 ,(1995) , 10.1128/AEM.61.9.3202-3207.1995
Alvaro Belenguer, Grietje Holtrop, Sylvia H. Duncan, Susan E. Anderson, A. Graham Calder, Harry J. Flint, Gerald E. Lobley, Rates of production and utilization of lactate by microbial communities from the human colon. FEMS Microbiology Ecology. ,vol. 77, pp. 107- 119 ,(2011) , 10.1111/J.1574-6941.2011.01086.X
H. M. HAMER, D. JONKERS, K. VENEMA, S. VANHOUTVIN, F. J. TROOST, R.-J. BRUMMER, Review article: the role of butyrate on colonic function Alimentary Pharmacology & Therapeutics. ,vol. 27, pp. 104- 119 ,(2007) , 10.1111/J.1365-2036.2007.03562.X
Harry J. Flint, Edward A. Bayer, Marco T. Rincon, Raphael Lamed, Bryan A. White, Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis Nature Reviews Microbiology. ,vol. 6, pp. 121- 131 ,(2008) , 10.1038/NRMICRO1817
Fredrik Backhed, Ruth E Ley, Justin L Sonnenburg, Daniel A Peterson, Jeffrey I Gordon, Host-Bacterial Mutualism in the Human Intestine Science. ,vol. 307, pp. 1915- 1920 ,(2005) , 10.1126/SCIENCE.1104816
E. Carol McWilliam Leitch, Alan W. Walker, Sylvia H. Duncan, Grietje Holtrop, Harry J. Flint, Selective Colonization of Insoluble Substrates by Human Faecal Bacteria Environmental Microbiology. ,vol. 9, pp. 667- 679 ,(2007) , 10.1111/J.1462-2920.2006.01186.X
Alan W. Walker, Sylvia H. Duncan, Hermie J. M. Harmsen, Grietje Holtrop, Gjalt W. Welling, Harry J. Flint, The species composition of the human intestinal microbiota differs between particle‐associated and liquid phase communities Environmental Microbiology. ,vol. 10, pp. 3275- 3283 ,(2008) , 10.1111/J.1462-2920.2008.01717.X
Julien Tap, Stanislas Mondot, Florence Levenez, Eric Pelletier, Christophe Caron, Jean-Pierre Furet, Edgardo Ugarte, Rafael Muñoz-Tamayo, Denis L. E. Paslier, Renaud Nalin, Joel Dore, Marion Leclerc, Towards the human intestinal microbiota phylogenetic core Environmental Microbiology. ,vol. 11, pp. 2574- 2584 ,(2009) , 10.1111/J.1462-2920.2009.01982.X