Coinfection and clinical manifestations of tuberculosis in human immunodeficiency virus-infected and -uninfected adults at a teaching hospital, northwest Ethiopia.

摘要: Background and Purpose: The pattern of clinical presentations tuberculosis (TB) is reflected in the microbiological, radiological, histological characteristics disease. However, coinfection with human immunodeficiency virus (HIV) poses special diagnostic therapeutic challenges. This study was aimed at assessing manifestations TB patients or without HIV a hospital-based crosssectional Gondar, Ethiopia. Methods: diagnosed following standard clinical, bacteriological, procedures. serostatus checked by enzyme-linked immunosorbent assay. Results: included 257 patients, whom 52.1% were coinfected HIV. Pulmonary extrapulmonary 64.2% 35.8% respectively. No significant association found between sputum smear positivity serostatus. One-fifth reported hemoptysis. More than one-third had chest pain, >90% fever weight loss. Night sweats cough 86% 82.5%, Coarse crepitations most frequent auscultatory finding (33.9%). Sputum rate 26.8%. Cavitation significantly associated (odds ratio = 9.0, 95% confidence interval 2.4-34.1). Wasting, ≤5 months’ duration, crepitation, chronic diarrhea, herpes zoster scar HIV-positive serology. Conclusion: Coinfection very high TB. presence scar, coarse crepitations, duration may assist identifying infection.