Synthesis, Characterization, DNA-Binding Studies of Rare Earth Complexes With N-Phenyl Norcantharidin Acylamide Acid
作者： Wen-Zhong Zhu , Fan Zhang , Qiu-Yue Lin , Qing-Yuan Qi , Jie Feng
DOI: 10.1080/15533174.2011.615041
关键词:
摘要: Three novel complexes containing ligand of N-phenyl norcantharidin acylamide acid (HL = 3-phenyl carbamoyl-7-oxabicyclo [2.2.1] heptane-2-carboxylic acid, C14H15NO4) were synthesized and characterized by elemental analyses, conductivity measurement, IR spectra, thermogravimetric analysis. The general formulas the [RE(L)(NO3)(H2O)2]NO3·2H2O, (RE ˭ Y(III), Gd(III), Dy(III)). results indicated that oxygen atoms carbonyl, cyclic ether, carboxylate coordinated to RE (III), there was also one nitrate taking part in coordination. RE(III) HL formed 1:1 chelate suggested coordination number eight. interactions between DNA have been investigated means fluorescence viscosity, agarose gel electrophoresis. showed could bind modes partly intercalation. binding abilities with follow trend: Dy(III) complex > Gd(III) Y(III) comple...
sci-hub.se 参考文章(22)
邹嘉佳, 许玲, 王煦, 李荣昌, 尹富玲, Synthesis, Characterization and Antitumor Activity of Lanthanum （III） Complex with Demethylcantharidate 中国稀土学报：英文版. ,vol. 23, pp. 596- 599 ,(2005)
Kazuo Nakamoto, Infrared and Raman Spectra of Inorganic and Coordination Compounds ,(1978)
Timothy A. Hill, Scott G. Stewart, Benjamin Sauer, Jayne Gilbert, Stephen P. Ackland, Jennette A. Sakoff, Adam McCluskey, Heterocyclic substituted cantharidin and norcantharidin analogues--synthesis, protein phosphatase (1 and 2A) inhibition, and anti-cancer activity. Bioorganic & Medicinal Chemistry Letters. ,vol. 17, pp. 3392- 3397 ,(2007) , 10.1016/J.BMCL.2007.03.093
Wen-Zhong Zhu, Rui-Ding Hu, Qiu-Yue Lin, Xiao-Xia Wang, Xiao-Liang Zheng, Synthesis, DNA-binding and antiproliferative activity of N-(Nitrogen heterocyclic) norcantharidin acylamide acid Central European Journal of Chemistry. ,vol. 7, pp. 569- 575 ,(2009) , 10.2478/S11532-009-0058-3
Jacqueline K. Barton, Adrienne L. Raphael, Photoactivated stereospecific cleavage of double-helical DNA by cobalt(III) complexes Journal of the American Chemical Society. ,vol. 106, pp. 2466- 2468 ,(1984) , 10.1021/JA00320A058
Timothy A. Hill, Scott G. Stewart, Stephen P. Ackland, Jayne Gilbert, Benjamin Sauer, Jennette A. Sakoff, Adam McCluskey, Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluation. Bioorganic & Medicinal Chemistry. ,vol. 15, pp. 6126- 6134 ,(2007) , 10.1016/J.BMC.2007.06.034
Bao-dui Wang, Zheng-Yin Yang, Patrick Crewdson, Da-qi Wang, Synthesis, crystal structure and DNA-binding studies of the Ln(III) complex with 6-hydroxychromone-3-carbaldehyde benzoyl hydrazone. Journal of Inorganic Biochemistry. ,vol. 101, pp. 1492- 1504 ,(2007) , 10.1016/J.JINORGBIO.2007.04.007
Xin-Qian He, Qiu-Yue Lin, Rui-Ding Hu, Xiao-Hong Lu, Synthesis, characterization and DNA-binding studies on La(III) and Ce(III) complexes containing ligand of N-phenyl-2-pyridinecarboxamide. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. ,vol. 68, pp. 184- 190 ,(2007) , 10.1016/J.SAA.2006.11.012
Penumaka Nagababu, S. Satyanarayana, DNA binding and cleavage properties of certain ethylenediamine cobalt(III) complexes of modified 1,10-phenanthrolines Polyhedron. ,vol. 26, pp. 1686- 1692 ,(2007) , 10.1016/J.POLY.2006.12.027
Guang-Sheng Wang, Medical uses of mylabris in ancient China and recent studies Journal of Ethnopharmacology. ,vol. 26, pp. 147- 162 ,(1989) , 10.1016/0378-8741(89)90062-7