Minimally invasive nephrectomy for Wilms tumors in children - data from SIOP 2001

摘要: Abstract Purpose To analyse the surgical and oncological outcome of minimally invasive surgery (MIS) for tumor nephrectomy in Wilms (WT) patients. Methods WT patients from SIOP 2001 trial, undergoing MIS were analyzed with regard to demographic characterization, specifications, complications, outcome. Results There 24 children matching inclusion criteria. Median age at operation was 40.35 months (14.3–65.4). All received preoperative chemotherapy. volume 177.5 ml diagnosis (46.5–958) 73.0 ml (3.8–776). one complication (splenic injury), no intraoperative rupture occurred. Abdominal stage I 14, II 7, III 3 Adequate lymph node sampling performed only 2 One local relapse Event-free survival 23/24, overall 24/24, median follow up 47 months (2–114). Conclusions We present largest series so far nephrectomies nephroblastoma based on a multinational trial. Treatment results comparable those open surgery; however, experience operating surgeons generally high. Discipline inadequate. Based this analysis prospective study is planned by Renal Tumor Study Group.