Chemical composition and antimicrobial activity of Hyptis suaveolens Poit. seed oil from Uttarakhand State, India

摘要: The present study was carried out to identify the chemical composition and antimicrobial activity of Hyptis suaveolens Poit. seed oil from Kalagarh region (Uttarakhand State, India). Gas Chromatograph Mass Spectrum (GC-MS) analysis suggested high amounts (86.96 %) unsaturated fatty acids: linoleic acid (76.13 %), oleic (10.83 %) compared saturated acids i.e. palmitic (6.55 %), stearic (4.56 %) heptacosanoic (1.94 %) as main constituents. (1 mg/ml 0.125 mg/ml) detrimental growth bacterial fungal strains tested. Among them Salmonella typhi MTCC 531 (9.92 ± 0.08 mm), Pseudomonas aeruginosa 424 (10.22 ± 0.11 mm), Lactobacillus plantarum 2621 (10.92 ± 0.09 mm) Candida tropicalis 229 (8.11 ± 0.07 mm) were susceptible at lower concentration (0.125 %). Escherichia coli 443, Shigella flexnerii 1457 Vibrio vulnificus 1145 sensitive only higher concentrations (0.5 1 %) bioactivity 1 mg/ml against C. comparable Fluconazole control (25 μg). On contrary Enterococcus fecalis 439 Streptococcus 3378 resistant treatment. Minimum Inhibition Concentrations (MIC) found be 0.125 mg/ml for S. typhi, P. aeruginosa, L. tropicalis, while it 0.2 mg/ml leishmanii, aureus albicans. observations indicate that H. possess appreciable properties Gram negative bacteria tested can further studied mode action lead a natural antibiotic.