The development of standard stimulus animals for mouse (Mus musculus) aggression testing by means of olfactory bulbectomy

摘要: Abstract The usual round-robin technique employed in aggression testing with mice has several major deficiencies. A set of specifications is given for the ideal standard stimulus mouse, which would overcome these In a series seven experiments, we found that bilateral olfactory bulbectomy yielded animals very closely approximated our ideal. Bulbectomized elicit attack behaviour from normal males, almost never initiate an themselves, rarely fought back when attacked, and were homogeneous their capability to release behaviour. These findings obtained whether tested within few days after or 40 afterwards.