Fungal Lethality, Binding, and Cytotoxicity of Syringomycin-E
作者： A. J. De Lucca , T. J. Jacks , J. Takemoto , B. Vinyard , J. Peter
DOI: 10.1128/AAC.43.2.371
关键词:
摘要: Syringomycin-E (SE) was significantly lethal to Aspergillus and Fusarium species at between 1.9 7.8 μg/ml. SE complexed with the following fungal wall constituents (in order of binding): β-1,3-glucan > chitin mannan ergosterol = cholesterol. Cytotoxicity in HeLa cells proportional concentration, while amount required for cytotoxicity 3 20 times that needed kill 95% fungi tested.
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