Genatlas database, genes and development defects
作者： Jean Frézal
DOI: 10.1016/S0764-4469(99)80021-3
关键词:
摘要: This article aims to illustrate the potentialities of Genatlas database, taking, as an example, developmental genes and their associated diseases in man. These belong several categories intervening from first stages embryonic life. They operate at all steps cascades extracellular signaling activation target genes. Quite a number those have been identified man, which are orthologs previously described lower species. mapped increasing with anomalies. studies shed light on mechanisms congenital malformations. disclose large array genetic phenotypic heterogeneity high degree complexity.
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