Acyl Carrier Protein VIII. STUDIES OF ACYL CARRIER PROTEIN AND COENZYME A IN ESCHERICHIA COLI PANTOTHENATE OR β-ALANINE AUXOTROPHS

作者: A.W. Alberts , P. Roy Vagelos

DOI: 10.1016/S0021-9258(18)96417-3

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摘要: Abstract A pantothenate-requiring auxotroph and a β-alanine-requiring of Escherichia coli were grown in media supplemented with radioactive pantothenate or β-alanine, respectively. Analyses extracts these organisms showed that acyl carrier protein accounts for approximately 90% the radioactivity associated fraction. Studies indicate under conditions experiments coenzyme are major cellular constituents which contain pantothenate. In addition, it was found concentration is directly related to medium, whereas does not vary variety growth conditions.

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