2-(Substituted phenyl)oxazolo[4,5-b]pyridines and 2-(substituted phenyl)oxazolo[5,4-b]pyridines as nonacidic antiinflammatory agents.

作者: Robert L. Clark , Arsenio A. Pessolano , Bruce Witzel , Thomas Lanza , T. Y. Shen

DOI: 10.1021/JM00209A014

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摘要: Some 2-(substituted phenyl)oxazolo[4,5-b]pyridines and phenyl)oxazolo[5,4-b]pyridines have good antiinflammatory analgesic activity. A few possess activity comparable to phenylbutazone or indomethacin without producing the irritation in gastrointestinal tract that acidic compounds cause.

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