Influence of Gonadal Function on GH Secretion

摘要: In contrast to the relatively clear-cut sexually dimorphic secretory pattern in rodents, episodic growth hormone (GH) secretion humans is unpredictable, with exception of first cycle slow-wave sleep, thus making their clinical assessment particularly difficult. Nevertheless, it has been reported that spontaneous GH increased around puberty both male and female subjects, suggesting a facilitative role gonadal steroids (1,2). Increased serum testosterone levels during normal boys associated burst mass amplitude (3). Similarly, replacement hypogonadal number pulses (4). Finally, aging there an association between reduction decreased andro- genic activity (5). Taken together these findings suggest androgens play humans.