Cardiac muscle regeneration: lessons from development
作者： M. Mercola , P. Ruiz-Lozano , M. D. Schneider
DOI: 10.1101/GAD.2018411
关键词:
摘要: The adult human heart is an ideal target for regenerative intervention since it does not functionally restore itself after injury yet has a modest capacity that could be enhanced by innovative therapies. Adult cardiac cells with potential share gene expression signatures early fetal progenitors give rise to multiple cell types, suggesting the evolutionarily conserved regulatory networks drive embryonic development might also control aspects of regeneration. Here we discuss commonalities and regeneration, application rich developmental biology heritage achieve therapeutic regeneration heart.
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