Models of Genetic Regulatory Networks

作者: M. Schilstra , H. Bolouri

DOI: 10.1007/978-3-662-06369-9_8

关键词:

摘要: This chapter provides a short review of the modelling Genetic Regulatory Networks (GRNs). GRNs have basic requirement to model (at least) some parts biological system using kind logical formalism. They represent set all interactions among genes and their products for determining temporal spatial patterns expression genes. The origin regulation gene goes back Nobel-prize winning work Lwoff, Jacob Monod on mechanisms underlying behaviour bacterial viruses that switch between so-called lytic lysogenic states. Some circuit-based approaches such as Kauffman, Thomas, Shapiro Adam are discussed.

参考文章(48)
F. Dellaert, Randall D Beer, Toward an evolvable model of development for autonomous agent synthesis Proc. Artificial Life IV. ,(1994)
Stuart Kauffman, Gene regulation networks: a theory for their global structure and behaviors. Current Topics in Developmental Biology. ,vol. 6, pp. 145- 182 ,(1971) , 10.1016/S0070-2153(08)60640-7
Randall D. Beer, John C. Gallagher, Evolution and analysis of dynamical neural networks for agents integrating vision, locomotion, and short-term memory genetic and evolutionary computation conference. pp. 1273- 1280 ,(1999)
Alistair G Rust, Rod Adams, Stella George, Hamid Bolouri, Developmental evolution of an edge detecting retina international conference on artificial neural networks. pp. 561- 566 ,(1998) , 10.1007/978-1-4471-1599-1_84
Madeline A. Shea, Gary K. Ackers, The OR control system of bacteriophage lambda. A physical-chemical model for gene regulation. Journal of Molecular Biology. ,vol. 181, pp. 211- 230 ,(1985) , 10.1016/0022-2836(85)90086-5
Michael B. Elowitz, Stanislas Leibler, A synthetic oscillatory network of transcriptional regulators Nature. ,vol. 403, pp. 335- 338 ,(2000) , 10.1038/35002125
Denis Thieffry, René Thomas, Qualitative analysis of gene networks pacific symposium on biocomputing. pp. 77- 88 ,(1998)
Marc Kirschner, John C. Gerhart, Cells, Embryos and Evolution ,(1997)