Synthesis of aryl-substituted pyridines via cyclization of N,N-dialkylanilines with ketoxime carboxylates under metal-organic framework catalysis

摘要: Abstract Iron-organic framework Fe 3 O(BPDC) was synthesized, and subsequently utilized as an productive heterogeneous catalyst for the cyclization reaction of N,N -dialkylanilines with ketoxime carboxylates to produce aryl-substituted pyridines. This iron-organic demonstrated remarkably higher catalytic productivity synthesis pyridines compared numerous conventional homogeneous catalysts well MOF-based catalysts. It possible reuse iron-framework in transformation cycles without a noticeable decline activity. To our best knowledge, this is first approach towards from ketoximes.