Chapter 12 Coupling of microdialysis sampling with biosensing detection modes

摘要: Publisher Summary This chapter discusses the coupling of microdialysis sampling with biosensing detection modes. These analyses—also called “non-separation” techniques—are based on molecular recognition target analyte, which may form a complex bioreceptor, allowing its selective identification even in mixture. The reaction between analyte and bioreceptor produces physical or chemical output signal normally relayed to transducer, then generally converts it into an electrical signal, providing quantitative information analytical interest. In addition role as research tool, is becoming integral part neurointensive-care monitoring standard for drug-distribution studies course drug development. selectivity characteristic biosensors allows avoidance separation procedures after collection, thus improving overall analysis terms both instrumentation time required.