Effectiveness of acyclovir in the treatment of pityriasis rosea. A systematic review and meta-analysis.
作者： Milton Rodriguez-Zuniga , Natalie Torres , Herney Garcia-Perdomo
DOI: 10.1590/ABD1806-4841.20187252
关键词:
摘要: BACKGROUND There is a lack of evidence to support acyclovir administration in pityriasis rosea. OBJECTIVE To determine the efficacy patients with typical METHODS A systematic review and meta-analysis experimental studies was performed MEDLINE, SCOPUS, EMBASE others, from January 1990 October 2016 on for Random effect model used find pooled Risk Ratio. Outcomes, evaluated between weeks 1 8, were regression lesions, cessation decrease symptoms duration disease. Comparisons vs. placebo; symptomatic treatment; antibiotic; observation combined therapy (acyclovir plus treatment) treatment alone. RESULTS Seven papers analyzed 324 participants, which 159 received 165 controls. Acyclovir superior placebo complete lesions at week (Risk Ratio 5.72, CI95% 2.36-13.88). However, not 4 1.46, 0.93-2.29). Individual showed superiority control pruritus. STUDY LIMITATIONS We faced differences designs trials inconsistency reports. CONCLUSION Symptomatic reasonable option rosea, addition justified
anaisdedermatologia.org.br
sci-hub.se 参考文章(46)
Francesco Drago, Giulia Ciccarese, Francesco Broccolo, Emanuele Cozzani, Aurora Parodi, Pityriasis Rosea in Children: Clinical Features and Laboratory Investigations. Dermatology. ,vol. 231, pp. 9- 14 ,(2015) , 10.1159/000381285
Rachel Heslop, Helen Roberts, Deralie Flower, Vanessa Jordan, Interventions for men and women with their first episode of genital herpes Cochrane Database of Systematic Reviews. ,vol. 2013, pp. 0- 0 ,(2016) , 10.1002/14651858.CD010684.PUB2
Luisa Terraneo, Sebastiano A.G. Lava, Pietro Camozzi, Lorenzo Zgraggen, Giacomo D. Simonetti, Mario G. Bianchetti, Gregorio P. Milani, Unusual Eruptions Associated with Mycoplasma pneumoniae Respiratory Infections: Review of the Literature. Dermatology. ,vol. 231, pp. 152- 157 ,(2015) , 10.1159/000430809
NilayKanti Das, Kunal Roy, AmalKanti Das, Debabrata Bandyopadhyay, Anupam Das, Amrita Sil, Acyclovir in pityriasis rosea: An observer-blind, randomized controlled trial of effectiveness, safety and tolerability. Indian Dermatology Online Journal. ,vol. 6, pp. 181- 184 ,(2015) , 10.4103/2229-5178.156389
Antonio AT Chuh, Belen L Dofitas, Gabriela Comisel, Ludovic Reveiz, Vidya Sharma, Sarah E Garner, Fergus KM Chu, Interventions for pityriasis rosea Cochrane Database of Systematic Reviews. ,vol. 2019, ,(2007) , 10.1002/14651858.CD005068.PUB2
S Rassai, A Feily, N Sina, SA Abtahian, Low dose of acyclovir may be an effective treatment against pityriasis rosea: a random investigator-blind clinical trial on 64 patients. Journal of The European Academy of Dermatology and Venereology. ,vol. 25, pp. 24- 26 ,(2011) , 10.1111/J.1468-3083.2010.03676.X
S Valkova, M Trashlieva, P Christova, UVB phototherapy for Pityriasis rosea Journal of The European Academy of Dermatology and Venereology. ,vol. 18, pp. 111- 112 ,(2004) , 10.1111/J.1468-3083.2004.00803.X
F. Guarneri, S.P. Cannavò, P.L. Minciullo, S. Gangemi, Pityriasis rosea of Gibert: immunological aspects Journal of The European Academy of Dermatology and Venereology. ,vol. 29, pp. 21- 25 ,(2015) , 10.1111/JDV.12701
Antonio Chuh, Narrow band UVB phototherapy and oral acyclovir for pityriasis rosea. Photodermatology, Photoimmunology and Photomedicine. ,vol. 20, pp. 64- 65 ,(2004) , 10.1111/J.1600-0781.2004.00072.X
N. Frenkel, E. C. Schirmer, L. S. Wyatt, G. Katsafanas, E. Roffman, R. M. Danovich, C. H. June, Isolation of a new herpesvirus from human CD4+ T cells Proceedings of the National Academy of Sciences of the United States of America. ,vol. 87, pp. 748- 752 ,(1990) , 10.1073/PNAS.87.2.748