Porous silicon nitride ceramics designed for bone substitute applications

摘要: Abstract Porous silicon nitride ceramics having properties similar to the human trabecular bone have been sintered and characterized in order develop a material applicable as substitute. At first, was especially terms of pore structure which is, besides non-toxicity, most critical for acceptation The network highly porous is formed by interconnected large pores approximately 300–1000 μm. Similar nitride-based attained replica method with polyurethane sponge forming agent. were prepared two ways, namely air-sintered reaction-bonded nitride. materials using same methods samples. Both types ceramic fulfilled microstructural requirements bioapplications. Moreover, their non-cytotoxicity proved measuring yellow tetrazolium MTT proliferation assay fibroblast cell line.