Inhibition of excitatory neurotransmission with kynurenate reduces brain edema in neonatal anoxia
作者： Roger P. Simon , Richard S.K. Young , Steven Stout , Julie Cheng
DOI: 10.1016/0304-3940(86)90648-8
关键词:
摘要: Excitatory amino acid neurotransmitters have been implicated in fostering brain edema and neuronal death ischemia. As both of these processes are involved nervous system damage during neonatal anoxia, the effect blockade cell excitation with kynurenate upon water was studied following anoxic-ischemic injury rats. Such treatment attenuated immediately after, 24 h anoxia-ischemia.
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