DNA lesions and repair in trypanosomatids infection.

作者: Bruno M. Repolês , Carlos Renato Machado , Pilar T.V. Florentino

DOI: 10.1590/1678-4685-GMB-2019-0163

关键词:

摘要: Pathological processes such as bacterial, viral and parasitic infections can generate a plethora of responses as, but not restricted to, oxidative stress that be harmful to the host pathogen. This occurs when there is an imbalance between reactive oxygen species produced antioxidant factors in response infection. lead DNA lesions both infected cells well The effects on parasite several kinds damage, causing alterations parasite's metabolism; reaction sensitivity these are related metabolism life cycle each parasite. present review will discuss survival strategies developed by Trypanosoma cruzi, focusing repair mechanisms organisms throughout infection including relationship features, unique characteristics diseases.

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