HLA Haplotype Mismatch Transplants and Posttransplant Cyclophosphamide.
作者： Andrea Bacigalupo , Simona Sica
DOI: 10.1155/2016/7802967
关键词:
摘要: The use of high dose posttransplant cyclophosphamide (PT-CY) introduced by the Baltimore group approximately 10 years ago has been rapidly adopted worldwide and is becoming a standard for patients undergoing unmanipulated haploidentical (HAPLO) transplants. PT-CY used following nonmyeloablative as well myeloablative conditioning regimens, bone marrow or peripheral blood grafts, with malignant nonmalignant disorders. Retrospective comparisons HAPLO grafts conventional sibling unrelated donor have published suggest comparable outcome. current questions to be answered include donors transplant, possibly in context prospective randomized trial.
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core.ac.uk 参考文章(25)
Xu Zhang, Katelin Jackson, Stacey Brown, Michelle Ridgeway, Melhem Solh, Lawrence E. Morris, H. Kent Holland, Scott R. Solomon, Asad Bashey, Comparison of Outcomes of Hematopoietic Cell Transplants from T-Replete Haploidentical Donors Using Post-Transplantation Cyclophosphamide with 10 of 10 HLA-A, -B, -C, -DRB1, and -DQB1 Allele-Matched Unrelated Donors and HLA-Identical Sibling Donors: A Multivariable Analysis Including Disease Risk Index Biology of Blood and Marrow Transplantation. ,vol. 22, pp. 125- 133 ,(2016) , 10.1016/J.BBMT.2015.09.002
A Bacigalupo, A Dominietto, A Ghiso, C Di Grazia, T Lamparelli, F Gualandi, S Bregante, M T Van Lint, S Geroldi, S Luchetti, R Grasso, S Pozzi, N Colombo, E Tedone, R Varaldo, A M Raiola, Unmanipulated haploidentical bone marrow transplantation and post-transplant cyclophosphamide for hematologic malignanices following a myeloablative conditioning: An update Bone Marrow Transplantation. ,vol. 50, pp. 537- 539 ,(2015) , 10.1038/BMT.2015.93
Yu Wang, Dai-Hong Liu, Kai-Yan Liu, Lan-Ping Xu, Xiao-Hui Zhang, Wei Han, Huan Chen, Yu-Hong Chen, Feng-Rong Wang, Jing-Zhi Wang, Yu-Qian Sun, Xiao-Jun Huang, Long-term follow-up of haploidentical hematopoietic stem cell transplantation without in vitro T cell depletion for the treatment of leukemia: nine years of experience at a single center. Cancer. ,vol. 119, pp. 978- 985 ,(2013) , 10.1002/CNCR.27761
Y Reisner, N Kapoor, D Kirkpatrick, MS Pollack, S Cunningham-Rundles, B Dupont, MZ Hodes, RA Good, RJ O'Reilly, Transplantation for severe combined immunodeficiency with HLA-A,B,D,DR incompatible parental marrow cells fractionated by soybean agglutinin and sheep red blood cells. Blood. ,vol. 61, pp. 341- 348 ,(1983) , 10.1182/BLOOD.V61.2.341.341
Dolores Grosso, Sameh Gaballa, Onder Alpdogan, Matthew Carabasi, Joanne Filicko-O’Hara, Margaret Kasner, Ubaldo Martinez-Outschoorn, John L. Wagner, William O'Hara, Shannon Rudolph, Inna Chervoneva, Beth Colombe, Patricia Cornett Farley, Phyllis Flomenberg, Barbara Pro, Manish Sharma, Wenyin Shi, Mark Weiss, Neal Flomenberg, A two-step approach to myeloablative haploidentical transplantation: low nonrelapse mortality and high survival confirmed in patients with earlier stage disease. Biology of Blood and Marrow Transplantation. ,vol. 21, pp. 646- 652 ,(2015) , 10.1016/J.BBMT.2014.12.019
Luca Castagna, Roberto Crocchiolo, Sabine Furst, Stefania Bramanti, Jean El Cheikh, Barbara Sarina, Angela Granata, Elisa Mauro, Catherine Faucher, Bilal Mohty, Samia Harbi, Christian Chabannon, Carmelo Carlo-Stella, Armando Santoro, Didier Blaise, Bone Marrow Compared with Peripheral Blood Stem Cells for Haploidentical Transplantation with a Nonmyeloablative Conditioning Regimen and Post-transplantation Cyclophosphamide Biology of Blood and Marrow Transplantation. ,vol. 20, pp. 724- 729 ,(2014) , 10.1016/J.BBMT.2014.02.001
Javier Bolaños-Meade, Ephraim J. Fuchs, Leo Luznik, Sophie M. Lanzkron, Christopher J. Gamper, Richard J. Jones, Robert A. Brodsky, HLA-haploidentical bone marrow transplantation with posttransplant cyclophosphamide expands the donor pool for patients with sickle cell disease. Blood. ,vol. 120, pp. 4285- 4291 ,(2012) , 10.1182/BLOOD-2012-07-438408
Shannon R. McCurdy, Jennifer A. Kanakry, Margaret M. Showel, Hua-Ling Tsai, Javier Bolaños-Meade, Gary L. Rosner, Christopher G. Kanakry, Karlo Perica, Heather J. Symons, Robert A. Brodsky, Douglas E. Gladstone, Carol Ann Huff, Keith W. Pratz, Gabrielle T. Prince, Amy E. Dezern, Ivana Gojo, William H. Matsui, Ivan Borrello, Michael A. McDevitt, Lode J. Swinnen, B. Douglas Smith, Mark J. Levis, Richard F. Ambinder, Leo Luznik, Richard J. Jones, Ephraim J. Fuchs, Yvette L. Kasamon, Risk-stratified outcomes of nonmyeloablative, HLA-haploidentical BMT with high-dose posttransplantation cyclophosphamide Blood. ,vol. 125, pp. 3024- 3031 ,(2015) , 10.1182/BLOOD-2015-01-623991
S-Q Ji, H-R Chen, H-M Yan, H-X Wang, J Liu, P-y Zhu, M-h Xiao, C-Q Xun, Anti-CD25 monoclonal antibody (basiliximab) for prevention of graft-versus-host disease after haploidentical bone marrow transplantation for hematological malignancies. Bone Marrow Transplantation. ,vol. 36, pp. 349- 354 ,(2005) , 10.1038/SJ.BMT.1705046
Anna Maria Raiola, Alida Dominietto, Carmen di Grazia, Teresa Lamparelli, Francesca Gualandi, Adalberto Ibatici, Stefania Bregante, Maria Teresa Van Lint, Riccardo Varaldo, Anna Ghiso, Marco Gobbi, Angelo Michele Carella, Alessio Signori, Federica Galaverna, Andrea Bacigalupo, Unmanipulated haploidentical transplants compared with other alternative donors and matched sibling grafts. Biology of Blood and Marrow Transplantation. ,vol. 20, pp. 1573- 1579 ,(2014) , 10.1016/J.BBMT.2014.05.029