Synthetic viruses and uses thereof
作者： Francois-Loic Cosset , Charlotte Frisen , Jean-Loup Salzmann , David Klatzmann , Bertrand Bellier
DOI:
关键词:
摘要: The present invention relates to compositions and methods for producing an immune response or reaction, as well vaccines, kits, processes, cells uses thereof. This more particularly of using a synthetic viral particle produce, modify regulate in subject. In preferred embodiment, the is based, generally, on particles adjuvant and/or vehicle raise against selected antigen(s) epitopes, particular cellular humoral response.
google.de 参考文章(46)
Matthew A. Gonda, Gregory J. Tobin, Chimeric Gag pseudovirions ,(1997)
M Maurice, SJ Russell, F Cossett, S Mazur, Mkl Collins, A Salvetti, FJ Bullough, Efficient gene delivery to quiescent IL2-dependent cells by MLV-derived vectors harboring IL2 chimeric envelope glycoproteins Blood , 94 p. 410. (1999). ,(1999)
Annemiek J. M. L. van Rensen, Marca H. M. Wauben, Mayken C. Grosfeld‐Stulemeyer, Willem van Eden, Daan J. A. Crommelin, Liposomes with incorporated MHC class II/peptide complexes as antigen presenting vesicles for specific T cell activation. Pharmaceutical Research. ,vol. 16, pp. 198- 204 ,(1999) , 10.1023/A:1018864005620
Samuel C. Kayman, Han Park, Maya Saxon, Abraham Pinter, The hypervariable domain of the murine leukemia virus surface protein tolerates large insertions and deletions, enabling development of a retroviral particle display system Journal of Virology. ,vol. 73, pp. 1802- 1808 ,(1999) , 10.1128/JVI.73.3.1802-1808.1999
Benjamin Rovinski, Roy Persson, Michel H. Klein, Fei-Long Yao, Shi-Xian Cao, Non-infectious, replication-defective, self-assembling HIV-1 viral particles containing antigenic markers in the gag coding region ,(1994)
Patrice Yeh, Christophe Torrent, David Klatzmann, Jean-Loup Salzmann, Michel Perricaudet, Methods and compositions for producing viral particles Official Gazette of the United States Patent and Trademark Office Patents. ,(1999)
Xianqiang Li, Flossie Wong-Staal, June Kan-Mitchell, Use of lentiviral vectors for antigen presentation in dendritic cells ,(1998)
E Kondo, F Mammano, E A Cohen, H G Göttlinger, The p6gag domain of human immunodeficiency virus type 1 is sufficient for the incorporation of Vpr into heterologous viral particles. Journal of Virology. ,vol. 69, pp. 2759- 2764 ,(1995) , 10.1128/JVI.69.5.2759-2764.1995
Ludwig Deml, Ralf Wagner, Markus Graf, Kurt Bieler, Synthetic gagpol genes and their uses ,(2001)
Meike-Dorothee Von Laer, Retroviral hybrid vectors pseudotyped with LCMV glycoprotein ,(1999)