Liposomes with incorporated MHC class II/peptide complexes as antigen presenting vesicles for specific T cell activation.

作者: Annemiek J. M. L. van Rensen , Marca H. M. Wauben , Mayken C. Grosfeld‐Stulemeyer , Willem van Eden , Daan J. A. Crommelin

DOI: 10.1023/A:1018864005620

关键词:

摘要: Purpose. The purpose of this study was to design a well-characterized liposomal carrier system for multivalent antigen presentation in order activate T cells.

参考文章(28)
E. R. Unanue, M. L. Dustin, S. Ranganath, C. A. Nelson, N. J. Viner, D. A. A. Vignali, J. M. Miller, TCR-mediated adhesion of T cell hybridomas to planar bilayers containing purified MHC class II/peptide complexes and receptor shedding during detachment. Journal of Immunology. ,vol. 157, pp. 2014- 2021 ,(1996)
Ziv Reich, J. Jay Boniface, Daniel S. Lyons, Nina Borochov, Ellen J. Wachtel, Mark M. Davis, Ligand-specific oligomerization of T-cell receptor molecules Nature. ,vol. 387, pp. 617- 620 ,(1997) , 10.1038/42500
Wim Jiskoot, Tom Teerlink, E. Coen Beuvery, Daan J. A. Crommelin, Preparation of liposomes via detergent removal from mixed micelles by dilution. The effect of bilayer composition and process parameters on liposome characteristics. Pharmacy World & Science. ,vol. 8, pp. 259- 265 ,(1986) , 10.1007/BF01960070
Bishwajit Nag, Prabha V. Mukku, Subhashini Arimilli, Dung Phan, Shrikant V. Deshpande, Jeffrey L. Winkelhake, Antigenic peptide binding to MHC class II molecules at increased peptide concentrations. Molecular Immunology. ,vol. 31, pp. 1161- 1168 ,(1994) , 10.1016/0161-5890(94)90030-2
A.M.H. Boots, M.J. van Lierop, M.H.M. Wauben, P.J.S. van Kooten, E.J. Hensen, W. van Eden, CD4 rat x rat and mouse x rat T cell hybridomas produced by fusion of established T cell lines and clones to W/Fu (C58NT)D. Journal of Immunological Methods. ,vol. 144, pp. 1- 10 ,(1991) , 10.1016/0022-1759(91)90223-3
Daniel S Lyons, Stephanie A Lieberman, Johannes Hampl, J.Jay Boniface, Yueh-hsiu Chien, Leslie J Berg, Mark M Davis, A TCR Binds to Antagonist Ligands with Lower Affinities and Faster Dissociation Rates Than to Agonists Immunity. ,vol. 5, pp. 53- 61 ,(1996) , 10.1016/S1074-7613(00)80309-X
Carl H. June, Jeffrey A. Bluestone, Lee M. Nadler, Craig B. Thompson, The B7 and CD28 receptor families Immunology Today. ,vol. 15, pp. 321- 331 ,(1994) , 10.1016/0167-5699(94)90080-9