Rapid screening natural-origin lipase inhibitors from hypolipidemic decoctions by ultrafiltration combined with liquid chromatography–mass spectrometry

作者: Shun Xiao , Runru Yu , Ni Ai , Xiaohui Fan

DOI: 10.1016/J.JPBA.2014.11.022

关键词:

摘要: … A rapid and easy method by ultrafiltration HPLC–MS is developed to screen lipase … the ultrafiltration combined with the HPLC–MS was an efficient method for rapid screening active …

参考文章(28)
Yufeng Zhang, Shun Xiao, Lijuan Sun, Zhiwei Ge, Fengkai Fang, Wen Zhang, Yi Wang, Yiyu Cheng, Rapid screening of bioactive compounds from natural products by integrating 5-channel parallel chromatography coupled with on-line mass spectrometry and microplate based assays Analytica Chimica Acta. ,vol. 777, pp. 49- 56 ,(2013) , 10.1016/J.ACA.2013.03.028
Irena Melnikova, David Wages, Anti-obesity therapies. Nature Reviews Drug Discovery. ,vol. 5, pp. 369- 370 ,(2006) , 10.1038/NRD2037
Ranjith Munigunti, Vanisree Mulabagal, Angela I. Calderón, Screening of natural compounds for ligands to PfTrxR by ultrafiltration and LC-MS based binding assay. Journal of Pharmaceutical and Biomedical Analysis. ,vol. 55, pp. 265- 271 ,(2011) , 10.1016/J.JPBA.2011.01.033
Ya Yuan, Yuzhi Wang, Meidong Huang, Ran Xu, Huan Zeng, Chan Nie, Jinhuan Kong, Development and characterization of molecularly imprinted polymers for the selective enrichment of podophyllotoxin from traditional Chinese medicines. Analytica Chimica Acta. ,vol. 695, pp. 63- 72 ,(2011) , 10.1016/J.ACA.2011.04.007
Allan Svendsen, Lipase protein engineering Biochimica et Biophysica Acta. ,vol. 1543, pp. 223- 238 ,(2000) , 10.1016/S0167-4838(00)00239-9