Efficient generation of perfluoroalkyl radicals from sodium perfluoroalkanesulfinates and a hypervalent iodine(iii) reagent: mild, metal-free synthesis of perfluoroalkylated organic molecules.
作者： Ryu Sakamoto , Hirotaka Kashiwagi , Sermadurai Selvakumar , Shin A. Moteki , Keiji Maruoka
DOI: 10.1039/C6OB01245K
关键词:
摘要: This article describes an efficient method for the introduction of perfluoroalkyl groups into N-acrylamides, 2-isocyanides, olefins, and other heterocycles using radicals that were generated from reaction between sodium perfluoroalkanesulfinates a hypervalent iodine(III) reagent. approach represents simple, scalable perfluoroalkylation under mild metal-free conditions.
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