Consensus recommendations for the standardized histopathological evaluation and reporting after radical oesophago-gastrectomy (HERO consensus).

摘要: Background Variation in the approach, radicality, and quality of gastroesophageal surgery impacts patient outcomes. Pathological outcomes such as lymph node yield are routinely used surrogate markers surgical quality, but subject to significant variations histopathological evaluation reporting. A multi-society consensus group was convened develop evidence-based recommendations for standardized assessment cancer specimens. Methods comprised surgeons, pathologists, oncologists on behalf Association Upper Gastrointestinal Surgery Great Britain & Ireland. Literature reviewed 17 key questions. Draft were voted upon via an anonymous Delphi process. Consensus considered achieved where >70% participants agreement. Results 18 statements all Twelve strong regarding preparation nodes, margins, reporting methods made. Importantly, there 100% agreement that specimens should be reported using Royal College Pathologists Guidelines minimum acceptable dataset. In addition, two weak method duration specimen fixation Four topics lacked sufficient evidence no recommendation Conclusions These provide explicit guidance assessment, maximum benefit care standardize allow benchmarking improvement quality.