作者: Edward J. Hammond , Basim M. Uthman , Steven A. Reid , B. J. Wilder
DOI: 10.1111/J.1528-1157.1992.TB01752.X
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摘要: Summary: Evidence from studies of experimental animals indicates that electrical stimulation the vagus nerve alters EEGs under certain stimulus parameters. We report EEG effects in 9 patients with medically intractable seizures as part a clinical trial chronic vagal for control epilepsy. The mechanism action antiepileptic effect is unknown, and we believed analysis electrophysiologic would help elucidate brain areas affected. left neck was stimulated programmable implanted stimulator. Stimulation at various frequencies amplitudes had no noticeable on activity whether patient general anesthesia, awake, or asleep, but may interrupt ongoing ictal activity.