Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
作者： Xueping Qu , Jie Yu , Govind Bhagat , Norihiko Furuya , Hanina Hibshoosh
DOI: 10.1172/JCI20039
关键词:
摘要: … do not show increased autophagic protein degradation rates … In rat liver carcinogenesis models, autophagic activity is … liver is a major site of nutrient starvation–induced autophagy (…
sci-hub.se 参考文章(70)
Laurie Elit, CCI-779 Wyeth. Current opinion in investigational drugs. ,vol. 3, pp. 1249- 1253 ,(2002)
Peter J Houghton, Shile Huang, Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic. Current opinion in investigational drugs. ,vol. 3, pp. 295- 304 ,(2002)
R. Dalla-Favera, A. Migliazza, C.-C. Chang, H. Niu, L. Pasqualucci, M. Butler, Q. Shen, G. Cattoretti, Molecular Pathogenesis of B Cell Malignancy: the Role of BCL-6 Current Topics in Microbiology and Immunology. ,vol. 246, pp. 257- 265 ,(1999) , 10.1007/978-3-642-60162-0_32
Ewald R. Weibel, Stereological Principles for Morphometry in Electron Microscopic Cytology International Review of Cytology. ,vol. 26, pp. 235- 302 ,(1969) , 10.1016/S0074-7696(08)61637-X
EFC Blommaart, JJFP Luiken, AJ Meijer, Autophagic proteolysis: Control and specificity Histochemical Journal. ,vol. 29, pp. 365- 385 ,(1997) , 10.1023/A:1026486801018
Fujio Kasumi, Satoru Sagae, Ryuichi Kudo, Johji Inazawa, Sumiko Koi, Kiichiro Noda, Hiroko Saito, Junko Saito, Yusuke Nakamura, Susumu Saito, Detailed Deletion Mapping of Chromosome 17q in Ovarian and Breast Cancers: 2-cM Region on 17q21.3 Often and Commonly Deleted in Tumors Cancer Research. ,vol. 53, pp. 3382- 3385 ,(1993)
Matthew L. Fero, Erin Randel, Kay E. Gurley, James M. Roberts, Christopher J. Kemp, The murine gene p27Kip1 is haplo-insufficient for tumour suppression Nature. ,vol. 396, pp. 177- 180 ,(1998) , 10.1038/24179
Kristy Brown, Beth Levine, Xiao Huan Liang, Jie Yu, Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function Cancer Research. ,vol. 61, pp. 3443- 3449 ,(2001)
Kenneth V. Honn, Wael Sakr, Alicia Salkowski, David J. Grignon, Arthur T. Porter, Alex Zacharek, Xiang Gao, Loss of Heterozygosity of the BRCA1 and Other Loci on Chromosome 17q in Human Prostate Cancer Cancer Research. ,vol. 55, pp. 1002- 1005 ,(1995)
Xiao Huan Liang, Linda K. Kleeman, Hui Hui Jiang, Gerald Gordon, James E. Goldman, Gail Berry, Brian Herman, Beth Levine, Protection against Fatal Sindbis Virus Encephalitis by Beclin, a Novel Bcl-2-Interacting Protein Journal of Virology. ,vol. 72, pp. 8586- 8596 ,(1998) , 10.1128/JVI.72.11.8586-8596.1998