Interaktion einer PDZ‐Proteindomäne mit einer synthetischen Bibliothek aller C‐Termini humaner Proteine
作者： Ulrich Hoffmüller , Michael Russwurm , Frank Kleinjung , Jennifer Ashurst , Hartmut Oschkinat
DOI: 10.1002/(SICI)1521-3757(19990712)111:13/14<2180::AID-ANGE2180>3.0.CO;2-G
关键词:
摘要: Neue Wechselwirkungspartner einer PDZ-Proteindomane konnten anhand Bibliothek identifiziert werden, die aus allen bekannten C-terminalen Peptiden („P” in der schematischen Darstellung) humaner Proteine besteht. Die bestand ortsgerichtet an eine Cellulosemembran gebundenen, invertierten Peptiden.
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