Uptake of Antigens from the Intestine by Dendritic Cells
作者： GORDON MacPHERSON , SIMON MILLING , ULF YRLID , LESLEY COUSINS , EMMA TURNBULL
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摘要: The intestinal immune system responds to ingested antigens in a variety of ways, ranging from tolerance full immunity. How T cells are instructed make these differential responses is still unclear. Dendritic (DCs) sample enteric the lamina propria and Peyer's patches, transport them within patch or mesenteric nodes where they presented lymphocytes. It probable that DCs also transmit information influences outcome cell activation, but nature this factors intestine regulate DC behavior properties far clear. We have developed model rat permits analysis actually process migration nodes. In paper we will review those aspects our research relate antigen uptake discuss context other experimental systems.
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