Photic regulation of peptides located in the ventrolateral subdivision of the suprachiasmatic nucleus of the rat: daily variations of vasoactive intestinal polypeptide, gastrin-releasing peptide, and neuropeptide Y
作者： K Shinohara , K Tominaga , Y Isobe , ST Inouye
DOI: 10.1523/JNEUROSCI.13-02-00793.1993
关键词:
摘要: We have determined, by enzyme immunoassay, daily and circadian patterns of the concentrations three peptides, which are located in ventrolateral subdivision suprachiasmatic nucleus (SCN): vasoactive intestinal polypeptide (VIP), gastrin-releasing peptide (GRP), neuropeptide Y (NPY). The contents VIP GRP, synthesized SCN, did not show rhythms constant darkness (DD). Under light-dark (LD) conditions, GRP content increased decreased over course light period then gradually recovered during dark period. Responsiveness these peptides to suggests that may transmit visual information on duration illumination. NPY, is transported from intergeniculate leaflet lateral geniculate body, showed a rhythm with peak at time 12 hr DD. This endogenous was remarkably modulated photic stimulation. LD NPY SCN exhibited bimodal peaks both dark-light transition points. Thus, convey transitions. All results indicate levels VIP, mainly regulated stimulation suggest involved mediation pacemaker.
sci-hub.se 参考文章(27)
HE Albers, SY Liou, EG Stopa, RT Zoeller, Interaction of colocalized neuropeptides: functional significance in the circadian timing system. The Journal of Neuroscience. ,vol. 11, pp. 846- 851 ,(1991) , 10.1523/JNEUROSCI.11-03-00846.1991
Meena Jhanwar-Uniyal, Bernard Beck, Claude Burlet, Sarah F. Leibowitz, Diurnal rhythm of neuropeptide Y-like immunoreactivity in the suprachiasmatic, arcuate and paraventricular nuclei and other hypothalamic sites. Brain Research. ,vol. 536, pp. 331- 334 ,(1990) , 10.1016/0006-8993(90)90045-D
Setsuji Hisano, Mika Chikamori-Aoyama, Shinsuke Katoh, Yasuaki Kagotani, Shigeo Daikoku, Kazuo Chihara, Suprachiasmatic nucleus neurons immunoreactive for vasoactive intestinal polypeptide have synaptic contacts with axons immunoreactive for neuropeptide Y: an immunoelectron microscopic study in the rat. Neuroscience Letters. ,vol. 88, pp. 145- 150 ,(1988) , 10.1016/0304-3940(88)90116-4
Martha Ulbrick Gillette, Steven M Reppert, None, The hypothalamic suprachiasmatic nuclei: circadian patterns of vasopressin secretion and neuronal activity in vitro. Brain Research Bulletin. ,vol. 19, pp. 135- 139 ,(1987) , 10.1016/0361-9230(87)90176-6
BRUCE D. KOCH, AGNES SCHONBRUNN, The somatostatin receptor is directly coupled to adenylate cyclase in GH4C1 pituitary cell membranes. Endocrinology. ,vol. 114, pp. 1784- 1790 ,(1984) , 10.1210/ENDO-114-5-1784
Andre´ Morin, Luc Denoroy, Michel Jouvet, Daily variations in concentration of vasoactive intestinal polypeptide immunoreactivity in discrete brain areas of the rat. Brain Research. ,vol. 538, pp. 136- 140 ,(1991) , 10.1016/0006-8993(91)90387-B
Shigenobu Shibata, Robert Y. Moore, Neuropeptide Y and Vasopressin Effects on Rat Suprachiasmatic Nucleus Neurons In Vitro Journal of Biological Rhythms. ,vol. 3, pp. 265- 276 ,(1988) , 10.1177/074873048800300305
Junichi Takeuchi, Hiroaki Nagasaki, Kazuyuki Shinohara, Shin-Ichi T. Inouye, A circadian rhythm of somatostatin messenger RNA levels, but not of vasoactive intestinal polypeptide/peptide histidine isoleucine messenger RNA levels in rat suprachiasmatic nucleus. Molecular and Cellular Neuroscience. ,vol. 3, pp. 29- 35 ,(1992) , 10.1016/1044-7431(92)90005-M
Anthony N. van den Pol, The hypothalamic suprachiasmatic nucleus of rat: Intrinsic anatomy The Journal of Comparative Neurology. ,vol. 191, pp. 661- 702 ,(1980) , 10.1002/CNE.901910410
Shigenobu Shibata, Yuh Liou Shyh, Showa Ueki, Yutaka Oomura, Influence of environmental light-dark cycle and enucleation on activity of suprachiasmatic neurons in slice preparations. Brain Research. ,vol. 302, pp. 75- 81 ,(1984) , 10.1016/0006-8993(84)91286-1