Blood sugar regulation in the hagfish, Myxine glutinosa

摘要: No decrease in blood glucose levels was found to occur fasting Myxine glutinosa over a 3-week period. After loading at 8°C the values showed maximum 1–2 hours after injection and return normal within days. About 15% of injected dose excreted. Crude hagfish insulin an approximate 5 IU/kg evoked hypoglycemia 2–3 days similar slow hypoglycemic response also obtained high doses ox insulin. In spite these findings, indicating that may control sugar levels, isletectomy did not evoke any hyperglycemia or force-fed hagfish, glucose-loading curve isletectomized fell range glucose-loaded hagfish. Hypophysectomy cause lasting hypo- hyperglycemic (in 3 weeks observation time), nor microscopical changes islets, but only transient rise which ascribed mechanical trauma hypothalamic region. A reaction for about 18 nonspecific injections, such as filtered sea water distilled water. The administration adrenalin, glucagon, thyroxine, pig corticotropin, thyrotropin, sheep prolactin containing growth hormone case above some morphological signs efficacy mammalian homones