Blood Oxidative Stress Levels in Workers Exposed to Respirable Crystalline Silica in the West of Iran

摘要: Background: Occupational exposure to crystalline silica is still an important health problem, especially in developing countries. Exposure may be associated with the induction of toxic oxidative stress. Objectives: This study was conducted assess stress biomarkers workers exposed respirable (RCS) Hamadan city, west Iran. Methods: descriptive-analytical on two groups selected from four industries and unexposed office 2017. The analysis RCS air samples done by NIOSH method No. 7602. Malondialdehyde (MDA), total antioxidant capacity (TAC), catalase (CAT) activity were measured serum samples. Results: In this study, 48 healthy 47 as controls selected. mean MDA levels (26.91 ± 14.26 nmol/mL) CAT (10.83 5.06 U/mL) higher group than (P < 0.001). However, no statistically significant difference observed TAC between correlation biomarker subjects. Conclusions: Although there a groups, according other results our it not possible claim that are appropriate biological indices for monitoring occupational settings. Therefore, we require comprehensive aspects research field.