Quantitation of small molecules using high-resolution accurate mass spectrometers - a different approach for analysis of biological samples.
作者： Nanyan Rena Zhang , Sean Yu , Philip Tiller , Suzie Yeh , Elizabeth Mahan
DOI: 10.1002/RCM.3975
关键词:
摘要: … Histogram of the LTQ-Orbitrap operating in full scan mode across a regular chromatographic peak using a mass resolution of 15 000 and in a scan range of 250–550 Da. …
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Zongwei Cai, Achintya K. Sinhababu, Stephanie Harrelson, Simultaneous quantitative cassette analysis of drugs and detection of their metabolites by high performance liquid chromatography/ion trap mass spectrometry Rapid Communications in Mass Spectrometry. ,vol. 14, pp. 1637- 1643 ,(2000) , 10.1002/1097-0231(20000930)14:18<1637::AID-RCM73>3.0.CO;2-2
Tobias Kind, Oliver Fiehn, Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry BMC Bioinformatics. ,vol. 8, pp. 105- 105 ,(2007) , 10.1186/1471-2105-8-105
Thomas R. Covey, Edgar D. Lee, Jack D. Henion, High-speed liquid chromatography/tandem mass spectrometry for the determination of drugs in biological samples Analytical Chemistry. ,vol. 58, pp. 2453- 2460 ,(1986) , 10.1021/AC00125A022
C.M. Chavez-Eng, M.L. Constanzer, B.K. Matuszewski, Simultaneous determination of Aprepitant and two metabolites in human plasma by high-performance liquid chromatography with tandem mass spectrometric detection Journal of Pharmaceutical and Biomedical Analysis. ,vol. 35, pp. 1213- 1229 ,(2004) , 10.1016/J.JPBA.2004.03.020
Ivana Bobeldijk, Maarten Hekman, Jitske de Vries-van der Weij, Leon Coulier, Raymond Ramaker, Robert Kleemann, Teake Kooistra, Carina Rubingh, Andreas Freidig, Elwin Verheij, Quantitative profiling of bile acids in biofluids and tissues based on accurate mass high resolution LC-FT-MS: compound class targeting in a metabolomics workflow. Journal of Chromatography B. ,vol. 871, pp. 306- 313 ,(2008) , 10.1016/J.JCHROMB.2008.05.008
Nanyan Zhang, Amy Yang, John Douglas Rogers, Jamie J Zhao, Quantitative analysis of simvastatin and its β-hydroxy acid in human plasma using automated liquid–liquid extraction based on 96-well plate format and liquid chromatography-tandem mass spectrometry Journal of Pharmaceutical and Biomedical Analysis. ,vol. 34, pp. 175- 187 ,(2004) , 10.1016/J.JAPNA.2003.08.016
Hisanori Hara, Takashi Uchimura, Naotsugu Akashi, Tomoyoshi Naganuma, Tetsushi Aizawa, Yusuke Nagae, Naoki Masuda, Simultaneous analytical method for the determination of TCH346 and its four metabolites in human plasma by liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry. ,vol. 18, pp. 377- 384 ,(2004) , 10.1002/RCM.1349
G. K. Poon, G. Kwei, R. Wang, K. Lyons, Q. Chen, V. Didolkar, C. E. C. A. Hop, Integrating qualitative and quantitative liquid chromatography/tandem mass spectrometric analysis to support drug discovery. Rapid Communications in Mass Spectrometry. ,vol. 13, pp. 1943- 1950 ,(1999) , 10.1002/(SICI)1097-0231(19991015)13:19<1943::AID-RCM736>3.0.CO;2-P
Richard A Scheltema, Anas Kamleh, David Wildridge, Charles Ebikeme, David G Watson, Michael P Barrett, Ritsert C Jansen, Rainer Breitling, None, Increasing the mass accuracy of high-resolution LC-MS data using background ions: a case study on the LTQ-Orbitrap. Proteomics. ,vol. 8, pp. 4647- 4656 ,(2008) , 10.1002/PMIC.200800314
Luc Alexis Leuthold, Chantal Grivet, Mark Allen, Mark Baumert, Gérard Hopfgartner, Simultaneous selected reaction monitoring, MS/MS and MS3 quantitation for the analysis of pharmaceutical compounds in human plasma using chip‐based infusion Rapid Communications in Mass Spectrometry. ,vol. 18, pp. 1995- 2000 ,(2004) , 10.1002/RCM.1587