IN VITRO HISTAMINE RELEASE FROM RAT PERITONEAL CELLS BY BETA-MERCAPTOETHYLAMINE AND CYSTAMINE

摘要: Cystamine and beta - mercaptoethylamine (MEA) induced a release of histamine from suspensions peritoneal cells the rat. The response to cystamine was proportional logarithm concentration over range 10-4 M 10-2 but MEA increased then decreased with increasing concentrations. percentage released in both time incubation 20 90 minutes. Aminoethanethiosulfuric acid at comparable concentrations did not induce cells. MEA rapidly converted cell suspensions. evidence supports hypothesis that MEA, vitro vivo, is due formed MEA.