Subpial transection surgery for epilepsy.

摘要: BACKGROUND Nearly 30% of patients with epilepsy continue to have seizures despite using several antiepileptic drugs (AEDs). Such are regarded as having refractory, or uncontrolled, epilepsy. While there is no universally accepted definition medically epilepsy, for the purposes this review we will consider drug resistant if they failed respond a minimum two AEDs. Specialists that early surgical intervention may prevent at younger age, which in turn improve intellectual and social status children. Many types surgery available treating refractory epilepsy; one such procedure known subpial transection. OBJECTIVES To assess effects transection focal-onset generalised tonic-clonic children adults. SEARCH METHODS For latest update searched following databases on 7 August 2018: Cochrane Register Studies (CRS Web), includes Epilepsy Group Specialized Central Controlled Trials (CENTRAL), MEDLINE (Ovid, 1946 06, 2018), ClinicalTrials.gov, WHO International Clinical Registry Platform (ICTRP). We imposed language restrictions. SELECTION CRITERIA considered all randomised quasi-randomised parallel-group studies, whether blinded non-blinded. DATA COLLECTION AND ANALYSIS Two authors (BK SR) independently screened trials identified by search. The same planned methodological quality studies. Had studies inclusion, author would extracted data, other verified data. MAIN RESULTS found relevant AUTHORS' CONCLUSIONS evidence support refute use Well-designed controlled needed guide clinical practice.