Application of dispersive liquid–liquid microextraction followed by gas chromatography/mass spectrometry as effective tool for trace analysis of organochlorine pesticide residues in honey samples

摘要: A dispersive liquid–liquid microextraction (DLLME) method followed by gas chromatography/mass spectrometry (GC/MS) was applied for the trace determination of organochlorine pesticides in honey samples. The type and volume organic extraction disperser solvents, pH, effect added salt content centrifuging time speed were optimized to find appropriate conditions. In DLLME, 30 µL 1,2-dibromomethane (serving as extractant) 1.5 mL acetonitrile disperser) applied. limit detection (3 s) quantification (10 all analytes interest (organochlorine pesticides) varied from 0.004 0.07 0.02 0.3 ng g−1, respectively. recovery ranged 91 100 %, enrichment factors 171 199. relative standard deviation <6 % intraday (n = 6) <8 interday 4) measurements. proposed DLLME–GC/MS confirmed be fast, simple perform, friendly environment suitable analysis pesticide residues at levels