Lipid lowering with thyroid hormone and thyromimetics
作者： Bo Angelin , Mats Rudling
DOI: 10.1097/MOL.0B013E3283402E9C
关键词:
摘要: Purpose of reviewTo summarize how thyroid hormones exert their effects on lipid metabolism through specific interaction with nuclear receptors, to review studies the new and selective thyromimetic drugs in animals humans identify important questions for future research
sci-hub.se 参考文章(46)
K. C. B. Tan, S. W. M. Shiu, A. W. C. Kung., Effect of Thyroid Dysfunction on High-Density Lipoprotein Subfraction Metabolism: Roles of Hepatic Lipase and Cholesteryl Ester Transfer Protein The Journal of Clinical Endocrinology and Metabolism. ,vol. 83, pp. 2921- 2924 ,(1998) , 10.1210/JCEM.83.8.4938
Yan-Yun Liu, Gregory A. Brent, Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation. Trends in Endocrinology and Metabolism. ,vol. 21, pp. 166- 173 ,(2010) , 10.1016/J.TEM.2009.11.004
Cecilia Gälman, Tomas Lundåsen, Alexei Kharitonenkov, Holly A. Bina, Mats Eriksson, Ingiäld Hafström, Maria Dahlin, Per Åmark, Bo Angelin, Mats Rudling, The Circulating Metabolic Regulator FGF21 Is Induced by Prolonged Fasting and PPARα Activation in Man Cell Metabolism. ,vol. 8, pp. 169- 174 ,(2008) , 10.1016/J.CMET.2008.06.014
Ivan Tancevski, Egon Demetz, Philipp Eller, Kristina Duwensee, Julia Hoefer, Christiane Heim, Ursula Stanzl, Andreas Wehinger, Kristina Auer, Regina Karer, Julia Huber, Wilfried Schgoer, Miranda Van Eck, Jonathan Vanhoutte, Catherine Fievet, Frans Stellaard, Mats Rudling, Josef R. Patsch, Andreas Ritsch, The Liver-Selective Thyromimetic T-0681 Influences Reverse Cholesterol Transport and Atherosclerosis Development in Mice PLOS ONE. ,vol. 5, pp. 8722- ,(2010) , 10.1371/JOURNAL.PONE.0008722
John D. Baxter, Paul Webb, Thyroid hormone mimetics: potential applications in atherosclerosis, obesity and type 2 diabetes Nature Reviews Drug Discovery. ,vol. 8, pp. 308- 320 ,(2009) , 10.1038/NRD2830
Ivan Tancevski, Andreas Wehinger, Egon Demetz, Julia Hoefer, Philipp Eller, Eva Huber, Ursula Stanzl, Kristina Duwensee, Kristina Auer, Wilfried Schgoer, Volker Kuhn, Catherine Fievet, Frans Stellaard, Mats Rudling, Bernhard Foeger, Josef R. Patsch, Andreas Ritsch, The thyromimetic T-0681 protects from atherosclerosis Journal of Lipid Research. ,vol. 50, pp. 938- 944 ,(2009) , 10.1194/JLR.M800553-JLR200
MITCHELL A. LAZAR, Thyroid hormone receptors : multiple forms, multiple possibilities Endocrine Reviews. ,vol. 14, pp. 184- 193 ,(1993) , 10.1210/EDRV-14-2-184
Bo Angelin, THERAPY FOR LOWERING LIPOPROTEIN (A) LEVELS Current Opinion in Lipidology. ,vol. 8, pp. 337- 341 ,(1997) , 10.1097/00041433-199712000-00003
Andrew C. Adams, Inna Astapova, ffolliott M. Fisher, Michael K. Badman, Katherine E. Kurgansky, Jeffrey S. Flier, Anthony N. Hollenberg, Eleftheria Maratos-Flier, Thyroid Hormone Regulates Hepatic Expression of Fibroblast Growth Factor 21 in aPPARα-dependent Manner Journal of Biological Chemistry. ,vol. 285, pp. 14078- 14082 ,(2010) , 10.1074/JBC.C110.107375
G. R. Thompson, A. K. Soutar, F. A. Spengel, A. Jadhav, S. J. Gavigan, N. B. Myant, Defects of receptor-mediated low density lipoprotein catabolism in homozygous familial hypercholesterolemia and hypothyroidism in vivo. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 78, pp. 2591- 2595 ,(1981) , 10.1073/PNAS.78.4.2591