Ultrastructure of the asexual blood stages of Plasmodium falciparum.

摘要: Plasmodium falciparum is the most deadly of human malaria parasites. The particular virulence this species derives from its ability to subvert physiology host during blood stages development. parasite grows and divides within erythrocytes, feeding on hemoglobin, remodeling cells so they adhere vessel walls. advent molecular transfection technology, coupled with optical microscopy fluorescent protein reporters, has greatly improved our understanding ways in which alters cell. However, a full interpretation information these studies requires similar advances knowledge ultrastructure parasite. Here we give an overview different electron techniques that have revealed fine structure at We present data some unusual organelles P. falciparum, particular, membrane structures are elaborated erythrocyte cytoplasm thought play important role trafficking proteins. discuss exciting whole cell imaging represent new frontier ultrastructure.