Anithrombotic prevention in vascular disease: bases for a new strategy in antithrombotic therapy

摘要: A tendency toward bleeding often undercuts the beneficial preventive effect of higher doses a single antithrombotic drug or combined therapy. Although high drugs may be necessary for optimal prevention, such therapy can also elicit more frequent bleeding. major could reversible event is likely to lead clinicians discontinue which in turn increase risk myocardial infarction, stroke, and cardiovascular death. Thus, prevent thrombotic events without complications, preferred approach might use anti-inflammatory addition first-line reduce inflammation thrombin formation atheroma. some preliminary data have been already published, confirm potential benefit acute coronary syndromes large prospective double-bind randomized trials are necessary.