BCL2 protein expression parallels its mRNA level in normal and malignant B cells

作者: Yulei Shen , Javeed Iqbal , James Z. Huang , Guimei Zhou , Wing C. Chan

DOI: 10.1182/BLOOD-2004-01-0243

关键词:

摘要: … We correlated BCL2 protein expression and BCL2 mRNA level measured by cDNA microarray in a series of previously reported DLBCL cases. Of the 3 different BCL2 clones (232714, …

参考文章(26)
M. Seto, U. Jaeger, R. D. Hockett, W. Graninger, S. Bennett, P. Goldman, S. J. Korsmeyer, Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma. The EMBO Journal. ,vol. 7, pp. 123- 131 ,(1988) , 10.1002/J.1460-2075.1988.TB02791.X
Motoi Hanada, Masayoshi Harigai, John C. Reed, Toshiyuki Miyashita, Identification of a p53-dependent negative response element in the bcl-2 gene Cancer Research. ,vol. 54, pp. 3131- 3135 ,(1994)
B E Wilson, E Mochon, L M Boxer, INDUCTION OF BCL-2 EXPRESSION BY PHOSPHORYLATED CREB PROTEINS DURING B-CELL ACTIVATION AND RESCUE FROM APOPTOSIS Molecular and Cellular Biology. ,vol. 16, pp. 5546- 5556 ,(1996) , 10.1128/MCB.16.10.5546
Hervé Husson, Elizabeth G. Carideo, Donna Neuberg, Joachim Schultze, Olivier Munoz, Peter W. Marks, John W. Donovan, Antoinette C. Chillemi, Peter O'Connell, Arnold S. Freedman, Gene expression profiling of follicular lymphoma and normal germinal center B cells using cDNA arrays. Blood. ,vol. 99, pp. 282- 289 ,(2002) , 10.1182/BLOOD.V99.1.282
Zenggang Pan, Yulei Shen, Cheng Du, Guimei Zhou, Andreas Rosenwald, Louis M. Staudt, Timothy C. Greiner, Timothy W. McKeithan, Wing C. Chan, Two Newly Characterized Germinal Center B-Cell-Associated Genes, GCET1 and GCET2, Have Differential Expression in Normal and Neoplastic B Cells American Journal of Pathology. ,vol. 163, pp. 135- 144 ,(2003) , 10.1016/S0002-9440(10)63637-1
Caroline Heckman, Evonne Mochon, Magdalena Arcinas, Linda M. Boxer, The WT1 Protein Is a Negative Regulator of the Normalbcl-2 Allele in t(14;18) Lymphomas Journal of Biological Chemistry. ,vol. 272, pp. 19609- 19614 ,(1997) , 10.1074/JBC.272.31.19609
John F. Kurland, Reinhard Kodym, Michael D. Story, Kevin B. Spurgers, Timothy J. McDonnell, Raymond E. Meyn, NF-κB1 (p50) Homodimers Contribute to Transcription of the bcl-2 Oncogene Journal of Biological Chemistry. ,vol. 276, pp. 45380- 45386 ,(2001) , 10.1074/JBC.M108294200
Klaus Rajewsky, Clonal selection and learning in the antibody system Nature. ,vol. 381, pp. 751- 758 ,(1996) , 10.1038/381751A0
H Martinez-Valdez, C Guret, O de Bouteiller, I Fugier, J Banchereau, Y J Liu, Human germinal center B cells express the apoptosis-inducing genes Fas, c-myc, P53, and Bax but not the survival gene bcl-2 Journal of Experimental Medicine. ,vol. 183, pp. 971- 977 ,(1996) , 10.1084/JEM.183.3.971