A systematic review of medication safety outcomes related to drug interaction software.
作者： Anne Holbrook , Kevin Wong , Savio K H Yu
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摘要: Background Adverse drug events (ADEs) represent an important problem for hospital and primary care. Software that detects potential adverse interactions has been widely implemented in effort to reduce the rate of ADEs. However, impact interaction detection software (DIS) on patient safety outcomes remains unknown. Objectives To systematically review literature DIS preventing determine effectiveness cost-effectiveness DIS. Methods A search MEDLINE, EMBASE, CINAHL, IPA Healthstar, using terms “Computer, or Decision Support” combined with “Drug Interactions, Drug Errors Monitoring” sought English language, post-1990 prospective studies examined (drug-drug) as intervention outcome. Relevant were analyzed a Bayesian meta-analysis approach. Results Of 5848 citations, only four met our inclusion criteria. Most excluded not measured prescriber attitudes, implementation success changes workflow. No study exclusively, rather component decision support software. these showed no significant difference event between control groups (relative risk 0.66, 95% CI 0.33 1.18). The posterior median Isquared was 52%.
参考文章(34)
Donald C. Spencer, Aaron Leininger, Rowell Daniels, Robert P. Granko, Remy R. Coeytaux, Effect of a computerized prescriber-order-entry system on reported medication errors. American Journal of Health-system Pharmacy. ,vol. 62, pp. 416- 419 ,(2005) , 10.1093/AJHP/62.4.0416
Tyken C. Hsieh, Gilad J. Kuperman, Tonushree Jaggi, Patricia Hojnowski-Diaz, Julie Fiskio, Deborah H. Williams, David W. Bates, Tejal K. Gandhi, Characteristics and Consequences of Drug Allergy Alert Overrides in a Computerized Physician Order Entry System Journal of the American Medical Informatics Association. ,vol. 11, pp. 482- 491 ,(2004) , 10.1197/JAMIA.M1556
Thomas K. Hazlet, Todd A. Lee, Philip D. Hansten, John R. Horn, Performance of Community Pharmacy Drug Interaction Software Journal of the American Pharmaceutical Association. ,vol. 41, pp. 200- 204 ,(2001) , 10.1016/S1086-5802(16)31230-X
Andrew M. Wilson, Lehana Thabane, Anne Holbrook, Application of data mining techniques in pharmacovigilance British Journal of Clinical Pharmacology. ,vol. 57, pp. 127- 134 ,(2003) , 10.1046/J.1365-2125.2003.01968.X
Harald Dormann, Uta Muth-Selbach, Sabine Krebs, Manfred Criegee-Rieck, Irmgard Tegeder, H. Thomas Schneider, Eckhart G. Hahn, Micha Levy, Kay Brune, Gerd Geisslinger, Incidence and costs of adverse drug reactions during hospitalisation: computerised monitoring versus stimulated spontaneous reporting. Drug Safety. ,vol. 22, pp. 161- 168 ,(2000) , 10.2165/00002018-200022020-00007
Andrew W Steele, Sheri Eisert, Joel Witter, Pat Lyons, Michael A Jones, Patricia Gabow, Eduardo Ortiz, The effect of automated alerts on provider ordering behavior in an outpatient setting. PLOS Medicine. ,vol. 2, pp. 864- 870 ,(2005) , 10.1371/JOURNAL.PMED.0020255
A. L. Potts, F. E. Barr, D. F. Gregory, L. Wright, N. R. Patel, Computerized Physician Order Entry and Medication Errors in a Pediatric Critical Care Unit Pediatrics. ,vol. 113, pp. 59- 63 ,(2004) , 10.1542/PEDS.113.1.59
Dan Degnan, Dave Merryfield, Steve Hultgren, Reaching out to clinicians: implementation of a computerized alert system. Journal for Healthcare Quality. ,vol. 26, pp. 26- 30 ,(2004) , 10.1111/J.1945-1474.2004.TB00533.X
Brent Mollon, Jaron JR Chong, Anne M Holbrook, Melani Sung, Lehana Thabane, Gary Foster, Features predicting the success of computerized decision support for prescribing: a systematic review of randomized controlled trials BMC Medical Informatics and Decision Making. ,vol. 9, pp. 11- 11 ,(2009) , 10.1186/1472-6947-9-11
S. Troy McMullin, Richard M. Reichley, Lesley A. Watson, Sherry A. Steib, Mark E. Frisse, Thomas C. Bailey, Impact of a Web-based clinical information system on cisapride drug interactions and patient safety. JAMA Internal Medicine. ,vol. 159, pp. 2077- 2082 ,(1999) , 10.1001/ARCHINTE.159.17.2077