CART - a chemical annotation retrieval toolkit
作者： Samy Deghou , Georg Zeller , Murat Iskar , Marja Driessen , Mercedes Castillo
DOI: 10.1093/BIOINFORMATICS/BTW233
关键词:
摘要: Motivation: Data on bioactivities of drug-like chemicals are rapidly accumulating in public repositories, creating new opportunities for research computational systems pharmacology. However, integrative analysis these data sets is difficult due to prevailing ambiguity between chemical names and identifiers a lack cross-references databases. Results: To address this challenge, we have developed CART, Chemical Annotation Retrieval Toolkit. As key functionality, it matches an input list into comprehensive reference space assign unambiguous identifiers. In unified space, bioactivity annotations can be easily retrieved from databases covering wide variety effects biological systems. Subsequently, CART determine enriched the set display tabular format interactive network visualizations, thereby facilitating data. Availability Implementation: available as Galaxy web service (cart.embl.de). Source code easy-to-install command line tool also obtained site. Contact: ed.lbme@krob Supplementary information: Supplementary at Bioinformatics online.
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