Small Hepatocellular Carcinoma—A Clinicopathological Study in Thirteen Patients

摘要: Abstract To investigate the diagnosis and clinicopathological features of hepatocellular carcinoma at its early stage, 13 patients with ≤3.0 × 3.0 cm in size (small carcinoma) were studied radionuclide scan, celiac arteriography, computed tomography, ultrasonography, peritoneoscopy. Most found from prospective studies hepatoma high-risk subjects asymptomatic, liver tests showing only mild abnormalities. Hepatitis B surface antigen was positive all except one who hepatitis core antibody positive. Serum α-fetoprotein level normal 3 remaining it increased to an extent far lower than advanced carcinoma. For detecting small tumors, arteriography superior scan or peritoneoscopy (detection rate: 95%, 94%, 89% vs. 16%, 12%, respectively). Small characterized as a hypoechoic shadow weak internal echoes on hypodense lesion hypervascular stain angiography. None these three examinations detected tumors every patient thus least two should be done avoid missing any tumor. Among them, real-time ultrasonography most practical for localizing could confirmed by ultrasound-guided biopsy. Ultrasonography indispensable identifying tumor during laparotomy patients. Ten had single The resected successfully 10 frequently surrounded thin fibrous capsule common cell type trabecular pattern.