Rats rapidly reject diets deficient in essential amino acids.

作者: Thomas J. Koehnle , Matthew C. Russell , Dorothy W. Gietzen

DOI: 10.1093/JN/133.7.2331

关键词:

摘要: Omnivores must obtain diets balanced with respect to amino acids support growth and protein synthesis. The standard paradigm used study behavioral responses acid deficiency combines deficient dietary novelty. objective of this was examine the effects on first meal rats without confounding We report a series five studies feeding behavior in rats. Rats were fed low for 5-7 d then exposed essential acids. consistently demonstrated recognition within by significant reduction duration, rejecting after just 12-16 min exposure. This is rapid effect acid-deficient

参考文章(15)
Clarence P. Berg, William C. Rose, Carl S. Marvel, TRYPTOPHANE AND GROWTH Journal of Biological Chemistry. ,vol. 85, pp. 207- 218 ,(1929) , 10.1016/S0021-9258(18)76990-1
Dorothy W. Gietzen, Neural mechanisms in the responses to amino acid deficiency. Journal of Nutrition. ,vol. 123, pp. 610- 625 ,(1993) , 10.1093/JN/123.4.610
A E Harper, N J Benevenga, R M Wohlhueter, Effects of ingestion of disproportionate amounts of amino acids. Physiological Reviews. ,vol. 50, pp. 428- 558 ,(1970) , 10.1152/PHYSREV.1970.50.3.428
Philip M.B. Leung, Dalmon M. Larson, Quinton R. Rogers, Food intake and preference of olfactory bulbectomized rats fed amino acid imbalanced or deficient diets Physiology & Behavior. ,vol. 9, pp. 553- 557 ,(1972) , 10.1016/0031-9384(72)90011-X
Thomas W. Castonguay, Lucia L. Kaiser, Judith S. Stern, Meal pattern analysis: artifacts, assumptions and implications ☆ Brain Research Bulletin. ,vol. 17, pp. 439- 443 ,(1986) , 10.1016/0361-9230(86)90252-2
James W Sharp, Linda J Magrum, Dorothy W Gietzen, Role of MAP kinase in signaling indispensable amino acid deficiency in the brain. Molecular Brain Research. ,vol. 105, pp. 11- 18 ,(2002) , 10.1016/S0169-328X(02)00380-7
S. Feurté, D. Tomé, D.W. Gietzen, P.C. Even, S. NicolaÏdis, G. Fromentin, Feeding patterns and meal microstructure during development of a taste aversion to a threonine devoid diet. Nutritional Neuroscience. ,vol. 5, pp. 269- 278 ,(2002) , 10.1080/10284150290032003
David A. Booth, Some characteristics of feeding during streptozotocin-induced diabetes in the rat. Journal of Comparative and Physiological Psychology. ,vol. 80, pp. 238- 249 ,(1972) , 10.1037/H0032968