New Cysteine Protease Inhibitors: Electrophilic (Het)arenes and Unexpected Prodrug Identification for the Trypanosoma Protease Rhodesain.

作者: Philipp Klein , Patrick Johe , Annika Wagner , Sascha Jung , Jonas Kühlborn

DOI: 10.3390/MOLECULES25061451

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摘要: Electrophilic (het) arenes can undergo reactions with nucleophiles yielding π-or Meisenheimer (σ-) complexes or the products of the SNAr addition/elimination reactions …

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