HLA-Bw15 and tuberculosis in a North American black population.

摘要: Peripheral blood lymphocytes from 60 black patients with Mycobacterium tuberculosis disease proved by culture and 100 healthy persons were HLA phenotyped using a standard lymphocytotoxicity test. Statistical analysis of the results showed that only Bw15 antigen had significantly increased frequency among when they compared to persons. Furthermore, examination manifestations demonstrated more far-advanced pulmonary cavitation than did without Bw15. These observations suggest may influence both susceptibility course disease.