Magnetic Resonance as a Tool for Pharmaco-Imaging

摘要: Imaging technologies in the nonclinical laboratory have been greatly bolstered by ever-improving methods available with magnetic resonance (MR) imaging. Small animal systems growing capability even while becoming more amenable to use biologists, revolutionizing how we can study pathophysiology and follow a drug or biologic therapy. MR’s ability characterize many anatomical physiological processes, based on their underlying influence tissue magnetization properties, has led, for example, discoveries psychopharmacology of attention deficit cognitive therapies recording changes oxygenation, blood flow vessel permeability acute studies, chronic remodeling water diffusion following This is short clearly abbreviated discussion applications MRI (and clinical) development laboratory, it meant introduce reader concepts this specific imaging modality likely offers most versatile all modalities as well being one very high resolution.