Evaluation of genetic stability of recombinant human factor VIII by peptide mapping and on-line mass spectrometric analysis.
作者： Marc J. Besman , Donald Shiba
关键词:
摘要: Purpose. The genetic stability of a recombinant human factor VIII (rhFVIII) product expressed in Chinese hamster ovary cells (Recombinate™) has been evaluated through comparisons the protein produced at beginning, middle and end typical production campaign.
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