作者: Jennifer G. Robinson , Anne C. Goldberg
DOI: 10.1016/J.JACL.2011.03.451
关键词:
摘要: Patients with familial hypercholesterolemias (FH) are at greatly increased lifetime risk of cardiovascular disease (CVD). If left untreated, most individuals FH will experience premature coronary heart (CHD) and/or stroke. The mean age onset a event in men is the early 40s and women 50s. Although fewer than 5% acute myocardial infarctions (AMI) occur #40 years age, associated 24-fold increase infarction by 40. In western countries, prevalence CVD middle-aged ranges from 22% to 39%. Therefore, all FH, regardless require lifestyle drug