Metabolic engineering of Escherichia coli into a versatile glycosylation platform: production of bio-active quercetin glycosides.
作者： Frederik De Bruyn , Maarten Van Brempt , Jo Maertens , Wouter Van Bellegem , Dries Duchi
DOI: 10.1186/S12934-015-0326-1
关键词:
摘要: Background Flavonoids are bio-active specialized plant metabolites which mainly occur as different glycosides. Due to the increasing market demand, various biotechnological approaches have been developed use Escherichia coli a microbial catalyst for stereospecific glycosylation of flavonoids. Despite these efforts, most processes still display low production rates and titers, render them unsuitable large-scale applications.
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